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Specific Substances

Alcohol
Nicotine
Marijuana
Opiates
Benzodiazepines
Stimulants
Inhalants
Hallucinogens & Designer Drugs

Supported by an unrestricted educational grant from
The Lawson Foundation

 

Inhalants

Volatile solvents, such as gasoline, glue, aerosol paints

Route, Duration

·                                                         Inhaled

Psychoactive Effects

·                                                         Similar to alcohol intoxication: disinhibition, euphoria

·                                                         Onset within minutes, duration several hours

Acute Medical Complications

·                                                         Dysrhythmias related to catecholamine release

·                                                         Asphyxia, aspiration

·                                                         Acute encephalopathy

·                                                         Psychosis, delirium

·                                                         Aggression, trauma

Symptoms of Withdrawal

·                                                         Similar to alcohol: tremor, anxiety

Treatment of Withdrawal

·                                                         Clinical presentation similar to alcohol withdrawal

·                                                         Treatment with benzodiazepines may be warranted

Chronic Complications

Neurological complications similar to alcohol, but more severe with earlier onset:

·                                                         Cerebellar degeneration 

·                                                         Peripheral neuropathy

·                                                         Cognitive deficits

Other complications:

·                                                         Hepatotoxicity

·                                                         Cardiomyopathy

Fetal Effects

·                                                         Case reports and animal studies have found neurodevelopmental delay and facial abnormalities similar to Fetal Alcohol Spectrum Disorder

Obstetrical Complications

·                                                         Spontaneous abortion, prematurity, low birth weight

Breastfeeding

·                                                         Advise women not to breastfeed within several hours of using

This site last edited: June 2008